BS3025 NUCLEAR MAGNETIC RESONANCE IN STRUCTURAL BIOLOGY

This course is for those pursuing the second Major in Structural Biology and aims to develop your fundamental understanding and fluency in practical applications of Nuclear Magnetic Resonance methods to determine 3D structures of biomolecules. It includes a study of the dynamics and intermolecular interactions both in solutions and in biological solids such as amyloids or filaments. The course aims to provide an overview of the power of NMR in applications ranging from the atomic resolution structures of proteins and ligand interactions to detailed 3D visualizations of live organisms. Since contemporary research in Structural Biology is rarely limited to the use of a single experimental method, understanding the fundamentals of NMR as one of the most important tools and integration with other methods like TEM and X-Ray are essential for those who are going to specialize in any field of Structural Biology.